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As a leading university hospital with a rich tradition, the Inselspital is part of the Insel Group and is a centre of medical expertise and high technology with an international reputation as well as being a first-class training and research centre.

Postdoc (Ph.D.) in Molecular Biology

Universitätsklinik für Frauenheilkunde
Laboratory of Endometriosis and Gynecological Oncology
100 % | in Bern
Entry by 01.09.2020 or by agreement
Temporary for 2 years with a possibility of extension
A Postdoctoral Research position in the laboratory of Endometriosis and Gynecological Oncology is available by September 1st 2020 to investigate the cellular diversity and mRNA expression in endometrium. The present project is supported by a grant from Innosuisse.
Who we are
Endometriosis is a prevalent and often painful disease characterised by the implantation and growth of endometrial epithelial and stromal cells outside the uterine cavity. The disease involves many disorders in the immunological, metabolic, hormonal systems, and unfortunately the decisive trigger has not yet been identified. It is nonetheless commonly accepted that endometriosis is usually found following retrograde menstruation. This means that during the period some of the menstrual blood flows through the fallopian tubes and reaches the abdominal cavity. This blood contains cells from the uterus that are viable and adhere to the peritoneum. This is why the lining of the endometrium, as the cellular source, has been and is still under intensive study. Our research laboratory is linked to the Department of Obstetrics and Gynaecology of the Inselspital which allows us to directly analyse tissues and fluids that are collected during the laparoscopic surgery. By comparing the results from patients with endometriosis with those of unaffected women we aim to identify, amongst others, the biological variations that may explain the occurrence, the course and the symptoms of endometriosis.
The proposed project is a funded collaboration between Inselspital and Scailyte AG, a Swiss Top100 startup company focusing on leveraging single-cell technologies and artificial intelligence (AI) data analytics to develop next-generation in vitro diagnostics.
Position objects - Requirements
We are looking for an independent and strongly motivated researcher with a PhD or MD/PhD degree, and experience in NGS and single-cell sequencing. Additional expertise for research projects involving human subjects, gynaecology, pain mechanisms, epithelial to mesenchymal transition or inflammation would be highly desirable. The ideal candidate is an adaptable team-player and has excellent communication and organizational skills. In this exciting role the candidate will have the unique opportunity to drive a discovery project addressing an enormous medically unmet-need using cutting edge genomic technology combined with machine learning based data analytics.
As post-doctorant you will take part into a project aiming to develop a non-invasive single-cell molecular in vitro diagnostic test for endometriosis. This work will consist mainly into preparation of single-cell suspensions, construction of gene expression libraries and analysis of the immune profile and transcriptome at the cellular level using the 10X genomics platform.
This project will provide multiple opportunities for collaborations and cross-disciplinary scientific exchanges. Meanwhile, the candidate should have excellent communication skills (particularly in English) and should be familiar with the constraints related to translational researches, in particular regarding deadlines. Aptitude to drive and maintain intra and inter team collaborations will be highly appreciated.
An interesting aspect for your carrier, you will have the possibility to develop your own research program taking advantage of our large biobank and of the expertise of our physicians.
The package
The position is limited to 2 years with a possibility of extension. To successfully reach your objectives dedicated technical support will be made available to you. The position will remain open until a suitable candidate will be recruited.

Please submit: CV, list of publications, motivation letter, description of your research interests, copies of PhD or MD/PhD degree and the names and telephone numbers of three referees

Contact

For further information please contact
Dr. Thomas Andrieu
Phone +41 31 632 73 82

Your application

Please only apply online.

The Insel Group

The Insel Group forms Switzerland's largest full-service medical care system -– from primary care through to state-of-the-art medicine -– that is available to everyone in the country. This ensures that every patient is treated at the most appropriate place for them and has access to the latest technologies, methods and medical options at all times.
Gebäude
Inselspital, Universitätsspital Bern
Freiburgstrasse, CH-3010 Bern
Schweiz
As a university hospital and the leading training institution in Canton Bern, the Inselspital offers training in 36 out of 44 possible medical disciplines. In their role as training organisations, the university clinics and institutes of the Insel Group are rated with an "A" – the highest classification.
In addition, the Insel Group offers practical training and CPD (continuous professional development) for all health professions up to specialist nursing care. It offers a broad range of vocational traineeships for its trainees, who currently number 300.
We are keen to foster personal development among our staff. Career opportunities and relevant models are transparent; CPD is provided with generous support.
Gender equality and the advancement of women are a big priority for us. Our career paths and models are designed so that part-time work and family responsibilities are no obstacles to taking on responsibility at our company.
Flexible working hours, part-time work and job-sharing. We are keen to accommodate the needs of our staff where the role and operating requirements of the hospital allow. This also applies to our executive-grade roles.
We offer 115 childcare places for around 180 children up to pre-school age at various locations. At the Inselspital site, there is also a group for babies from the fourth month and a private kindergarten.
As a family-friendly employer, the Insel Group provides generous schemes for unpaid leave, short remunerated breaks and parental leave in the event of the birth of a child or an adoption. Fathers also receive ten working days paid paternity leave. Extra days of leave are offered by way of a loyalty bonus from as early as the fifth year of service!
Bern and its region assume a central role in Switzerland. With its enviable infrastructure, rapid links to the country's major conurbations, proximity to urban and rural districts and variety of wonderful recreational areas, Bern and its environs offer an unusually high quality of life.
The social package we offer is far above the industry average. Our benefits are exceptional, particularly in the case of maternity leave, continued payment of salary in the event of sickness and accident, and full payment of daily sickness allowance or group health insurance premiums.
We provide medical excellence with a human touch and respect for one another. As a big business we create a unique family atmosphere through meaningful diversity within the Insel Group.
For us it is very important new employees undergo a well prepared and thorough induction. We give you detailed information about your new employer at a monthly welcome event and also provide tailored induction programmes in the clinics, institutes and administrative departments.
Every site operated by the Insel Group has one or more staff restaurants. Our staff appreciate the quality, variety and creativity of our catering, which has repeatedly won prestigious gastronomy prizes.
Innovations in medicine and research are only possible if we continue to develop. Rapid developments in the medical field bring about extraordinary processes of change – as well as prospects for individual development for you.
Humanity

Humanity

Respect and a high regard for the individual are central to everything we do.

Competence

Competence

We have confidence in our abilitiesand share our knowledge for the benefit of all our patients.

Quality

Quality

Our actions comply with the highest standards of quality and safety.

Innovation

Innovation

We seek new approaches as well as promote research and innovation.

Cooperation

Cooperation

We treat one another with respect and appreciation, foster professional cooperation and promote interdisciplinarity.

Integrity

Integrity

We are committed to our values and are guided by sincerity, transparency and dependability.

Facts

Facts and figures

  • 6 sites in the canton of Bern
  • Over 10,000 employees from around 80 countries
  • Over 300 trainees in 16 vocational fields
  • 15,185 placement/training weeks (at tertiary level, medical and other professions)
  • Around 500,000 patients, including over 60,750 inpatients
  • 1st class: the Inselspital is the leading Swiss university hospital in terms of patient satisfaction.
Facts and figures
University hospital (highly specialist care, all disciplines) University hospital (highly specialist care, all disciplines)
City hospital Tiefenau (comprehensive primary care and secondary care) City hospital Tiefenau (comprehensive primary care and secondary care)
Rural hospitals (primary care close to home) Rural hospitals (primary care close to home)
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